soluble (iou) and cross-resistance (medicine)

soluble (iou)

soluble adjective & noun. LME.
[Old & mod. French from late Latin solubilis, from Latin solvere SOLVE: see -UBLE.]
A. adjective.
Medicine.
a. Of the bowels etc.: free from constipation. Now rare or obsolete. LME.
b. Laxative. E16-E18.
Able or intended to be dissolved, esp. in water. Formerly also, able to be melted. LME.
soluble blue any of various water-soluble dyes that are di- and trisulphonic acid Derivatives of aniline blue, now used chiefly in papers and inks. soluble RNA = transfer RNA s.v. TRANSFER noun.
E. Ambler I gave her some soluble aspirin and left.
Able to be untied or loosed. rare. E17.
Able to be solved or explained. E18.
b. Math. = SOLVABLE 2b. E20.
Able to be resolved, reducible. E19.
O. W. Holmes Love is sparingly soluble in the words of men.
b. noun. A soluble constituent, esp. of a foodstuff. M20.

cross-resistance (medicine)

cross-resistance
<immunology, microbiology> Immunologic resistance to the pathogenic effects of a microorganism because of previous exposure to another species or type having cross reactive antigens.

This phenomenon is seen in microbes that acquire resistance to one drug through direct exposure and turn out to have resistance to one or more Other drugs to which it has not been exposed. Cross-resistance arises because the mechanism of resistance to several drugs is the same and arises through the identical genetic mutations.

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