See Also: Canavan-van Bogaert-Bertrand disease(medicine)
Disease, Canavan(health)
Canavan disease(medicine)
Canavan's disease(medicine)
Canavan disease(health)
van Bogaert encephalitis(medicine)
van Bogaert, Ludo(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Canavan, Myrtelle(medicine)
Canavan's sclerosis(medicine)

Canavan-van Bogaert-Bertrand disease (medicine)


Canavan-van Bogaert-Bertrand disease -->
Canavan's disease
Autosomal recessive degenerative disease of infancy; mostly in Jewish infants; onset typically within first 3-4 months of birth, consisting of blindness, psychomotor regression, enlarged head, optic atrophy, hypotonia, spasticity, increased N-acetylaspartic acid urinary excretion. MRI shows enlarged brain, decreased attenuation of cerebral and cerebellar white matter, and normal ventricles. Pathologically, there is increased brain volume and weight, and spongy degeneration in the subcortical white matter.

See: leukodystrophy.

Synonym: Canavan's sclerosis, Canavan-van Bogaert-Bertrand disease, spongy degeneration of infancy.