See Also: FDNB(medicine)
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FDNB (medicine)


FDNB -->
fluoro-2,4-dinitrobenzene


A reagent used to combine with the free NH2 group of the NH2-terminal amino acid residue in a peptide, thus marking this residue; the combined forms are known as DNP-proteins, Dnp-aminoacyl, etc., the fluorine having been replaced to leave a dinitrophenyl residue (DNP, Dnp, or N2Ph-) attached to the NH2 group.

Synonym: Sanger's reagent.

Acronym: FDNB