See Also: Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
glutathione(dictionary)
Glutathione(medicine)
Glutathione reductase(medicine)
glutathione disulfide(medicine)
oxidised glutathione(medicine)
glutathione transferase(medicine)
glutathione S-transferase(medicine)
glutathione synthase(medicine)
glutathione oxidase(medicine)

Glutathione (medicine)


glutathione
<biochemistry> The tripeptide _ glutamylcysteinylglycine. It contains an unusual peptide linkage between the _ carboxyl group of the glutamate side chain and the amine group of cysteine.

The concentration of glutathione in animal cells is _5mM and its sulphydryl group is kept largely in the reduced state. This allows it to act as a sulphydryl buffer, reducing any disulphide bonds formed within cytoplasmic proteins to cysteines. Hence, few, if any, cytoplasmic proteins contain disulphide bonds.

Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids and participates in leucotriene synthesis.