See Also: Hoffmann's muscular atrophy(medicine)
Werdnig-Hoffmann muscular atrophy(medicine)
Muscular atrophy(medicine)
muscular atrophy, spinal(medicine)
idiopathic muscular atrophy(medicine)
Atrophy, peroneal muscular(health)
infantile muscular atrophy(medicine)
ischemic muscular atrophy(medicine)
juvenile muscular atrophy(medicine)
progressive muscular atrophy(medicine)
Hoffmann's muscular atrophy (medicine)
Hoffmann's muscular atrophy -->
infantile spinal muscular atrophy
Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised.
Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy.
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