See Also: Marchiafava-Micheli anaemia(medicine)
Marchiafava-Micheli syndrome(medicine)
Micheli, Ferdinando(medicine)
Marchiafava, Ettore(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Marchiafava-Bignami disease(medicine)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
in fine(dictionary)
fine art(dictionary)
fine(3)(dictionary)

Marchiafava-Micheli anaemia (medicine) and fine(5) (iou)


Marchiafava-Micheli anaemia (medicine)


Marchiafava-Micheli anaemia -->
paroxysmal nocturnal haemoglobinuria


An infrequent disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterised by episodes of haemolytic anaemia, haemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly; red blood cells are usually macrocytic and vary considerably in size, but there is no evidence of spherocytosis, erythrophagocytosis, or abnormal leukocytes. The disorder is a result of an abnormality of the red cell membrane which makes the red cell unusually sensitive to lysis by complement.

Synonym: Marchiafava-Micheli anaemia, Marchiafava-Micheli syndrome.


fine(5) (iou)



fine noun1. ME.
[Old & mod. French fin from Latin finis end, (in medieval Latin) a sum to be paid on concluding a lawsuit.]
I. End.
Cessation, termination, conclusion. Now only in in fine below. ME.
in fine (a) in the end, at last; (b) finally, to sum up, in short.
The end of life, death. ME-M16.
The limit; extremity, an extreme case. LME-M19.
The end in view; an aim, a purpose. LME-E17.
A consequence, a result. E16-E17.
II.
Law. The final agreement or settlement of a suit; spec. the compromise of a fictitious or collusive suit for the possession of land, formerly used as a form of conveyance. obsolete exc. Hist. ME.
III. A fee, a penalty.
a. A penalty of any kind. arch. ME.
J. S. Blackie We stood for our faith, when our life was the fine.
b. A sum of money imposed as the penalty for breaking the law or a regulation. LME.
H. Hallam Fines to the amount of 85,000..were imposed on the Covenanters.
A sum of money offered or paid for exemption from punishment or as compensation for injury. ME-E17.
A fee paid for any privilege. LME-M18.
Hist. A fee paid to a feudal landlord by the tenant or vassal on the transfer or alienation of the tenancy. LME.
b. A sum of money paid by an incoming tenant in consideration of a low rent. E16.
Comb.: fine rolls Hist. rolls recording payments made to the Crown for the granting of privileges, land, etc.