See Also: mesothelioma:Peritoneal mesothelioma treatment(medicine)
mesothelioma:Pleural mesothelioma treatment(medicine)
Mesothelioma:Treatment(medicine)
mesothelioma:Statistics and outlook for mesothelioma(medicine)
mesothelioma:Tests for mesothelioma(medicine)
mesothelioma:Screening for mesothelioma(medicine)
mesothelioma:The stages of mesothelioma(medicine)
mesothelioma:Mesothelioma risks and causes(medicine)
mesothelioma:Further tests for mesothelioma(medicine)
mesothelioma:After your mesothelioma surgery(medicine)
Mesothelioma:Treatment (medicine)
Treatment
What treatment you undergo for mesothelioma depends on your health and certain aspects of your cancer, such as its stage and location. Unfortunately, mesothelioma often is an aggressive disease and for many people a cure won't be possible. Mesothelioma is usually diagnosed at an advanced stage — when it isn't possible to remove the cancer through surgery. Instead, your doctor may work to control your cancer and its signs and symptoms to make you more comfortable.
Discuss your treatment goals with your doctor. Some people want to do everything they can to treat their cancer, even if that means enduring side effects for a small chance of a cure. Others prefer treatments that make them comfortable so that they can live their remaining months as symptom-free as possible.
Mesothelioma treatment options may include surgery, radiation, chemotherapy and clinical trials.
Surgery
Surgeons work to remove mesothelioma from your body. Sometimes it isn't possible to remove all of the cancer. In those cases, surgery may help to reduce the signs and symptoms caused by mesothelioma spreading in your body. Surgical options may include:
Surgery to decrease fluid buildup. Pleural mesothelioma may cause fluid to build up in your chest, causing difficulty breathing. Surgeons insert a tube or catheter into your chest to drain the fluid. Surgeons may also inject medicine into your chest to prevent fluid from returning (pleurodesis).
Surgery to remove the tissue around the lung or abdomen. Surgeons may use scalpels and other surgical tools to remove the tissue lining the ribs and the lungs (pleurectomy) or the tissue lining the abdominal cavity (peritonectomy) in order to relieve signs and symptoms of mesothelioma.
Surgery to remove as much of the cancer as possible (debulking). If all of the cancer can't be removed, surgeons may attempt to remove as much as possible.
Surgery to remove a lung and the surrounding tissue. Removing the affected lung and the tissue that surrounds it may relieve signs and symptoms of pleural mesothelioma. This procedure also allows doctors to use higher doses of radiation against any remaining mesothelioma, since doctors won't need to worry about protecting your lung from damaging radiation.
Chemotherapy
Chemotherapy uses chemicals to kill cancer cells. Chemotherapy drugs travel throughout your body and kill rapidly growing cells. This works against cancer cells, but also affects other rapidly growing cells in your body, such as those in your hair follicles and those in your gastrointestinal system. Chemotherapy may slow the growth of pleural mesothelioma. Chemotherapy can be used before surgery (neoadjuvant chemotherapy) or after surgery (adjuvant chemotherapy) to reduce the signs and symptoms you may experience from mesothelioma.
People with peritoneal mesothelioma may receive adjuvant chemotherapy drugs that have been heated (hyperthermic chemotherapy). Rather than being distributed throughout the body, chemotherapy drugs are often injected directly into the abdominal cavity (intraperitoneal chemotherapy), where they can reach the peritoneal mesothelioma directly without injuring healthy cells in other parts of the body. This allows doctors to administer higher doses of chemotherapy drugs. Intraperitoneal chemotherapy may also be used to reduce the signs and symptoms of peritoneal mesothelioma that can't be removed through surgery.
Radiation therapy
Radiation therapy focuses high-energy radiation to a specific spot or spots on your body. Radiation may reduce signs and symptoms in people with pleural mesothelioma. Doctors aim radiation at the entire chest to obtain the best result. However, many sensitive organs reside in the chest, such as the heart, lungs and spinal cord, so doctors must use low doses of radiation to spare these organs. Radiation therapy is sometimes used after biopsy or surgery to prevent mesothelioma from spreading to the surgical incision.
Radiation therapy is used occasionally in people with peritoneal mesothelioma. Radiation may reduce signs and symptoms of mesothelioma.
Combination therapy
Surgery, chemotherapy and radiation therapy may be combined. This aggressive therapy can be grueling and may not be appropriate for everyone. Younger, healthier people and those with earlier stage mesothelioma may be more able to endure this treatment. Combination therapy has shown the most promise in treating mesothelioma. However, most people will eventually experience a recurrence of this cancer despite this aggressive treatment. Combination therapy has been used in both pleural mesothelioma and peritoneal mesothelioma.
Clinical trials
Clinical trials are studies of new mesothelioma treatment methods. People with mesothelioma may opt for a clinical trial for a chance to try new types of treatment. However, a cure isn't guaranteed. Carefully consider your treatment options and talk to your doctor about what clinical trials are open to you. Your participation in a clinical trial may help doctors better understand how to treat mesothelioma in the future.
Treatment for other types of mesothelioma
Pericardial mesothelioma and mesothelioma of the tunica vaginalis are very rare and can be very aggressive. Early-stage cancer may be removed through surgery. Doctors have yet to determine the best way to treat later stage cancers, though. Your doctor may recommend other treatments to improve your quality of life.
About mesothelioma
Mesothelioma
mesothelioma:What is mesothelioma?
mesothelioma:Mesothelioma risks and causes
mesothelioma:Screening for mesothelioma
mesothelioma:Mesothelioma symptoms
mesothelioma:Types of mesothelioma
mesothelioma:Tests for mesothelioma
mesothelioma:Further tests for mesothelioma
mesothelioma:The stages of mesothelioma
mesothelioma:Statistics and outlook for mesothelioma
mesothelioma:Pleural mesothelioma treatment
mesothelioma:Peritoneal mesothelioma treatment
mesothelioma:Which surgery for mesothelioma?
mesothelioma:Before your mesothelioma surgery
mesothelioma:What's new in mesothelioma
Mesothelioma:Introduction
Mesothelioma:Signs and symptoms
Mesothelioma:Causes
Mesothelioma:Risk factors
Mesothelioma:Screening and diagnosis
Mesothelioma:Complications
Mesothelioma:Treatment
Mesothelioma:Prevention
Mesothelioma:Coping skills
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