See Also: MyoD(medicine)
myod protein(medicine)
MyoD heavy chain kinase(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Medicine Lodge Memorial Hospital- Medicine Lodge(health)
Orthomolecular medicine (orthomolecular nutritional medicine, orthomolecular therapy)(health)
medicine(2)(dictionary)
medicine(dictionary)
medicine(encyclopedia)
medicine man(encyclopedia)

MyoD (medicine)


myoD
<molecular biology> Stands for myogenic determination.

MyoD was described as a master regulatory gene for the determination of muscle cells, but muscle determination is now thought to involve a family of genes. It is normally only expressed in myoblasts and skeletal muscle cells, but if transfected into cells will convert many differentiated cells into muscle cells. The myoD gene codes for the myoD protein which then switches on the the transcription of many muscle specific genes. MyoD is a member of a family of genes that all code for nuclear proteins which have a basic DNA binding motif and a helix loop helix dimerisation domain (bHLH or mHLH proteins, b=basic, m=myogenic). They bind to a consensus sequence CANNTG and can form homodimers or heterodimers with other members of the bHLH superfamily.