See Also: maturation-promoting factor(medicine)
epidermal growth factor receptor protein-tyrosine kinase(medicine)
M phase promoting factor(medicine)
leukocytosis-promoting factor(medicine)
maturation factor(medicine)
erythrocyte maturation factor(medicine)
protein-tyrosine kinase(medicine)
protein-tyrosine-phosphatase(medicine)
emb protein-tyrosine kinase(medicine)
NU-3 protein tyrosine phosphatase(medicine)

NU-3 protein tyrosine phosphatase (medicine) and maturation-promoting factor (medicine)


NU-3 protein tyrosine phosphatase (medicine)


NU-3 protein tyrosine phosphatase
<enzyme> The murine homolog of rat cam tyrosine phosphatase; has an extracellular cell-adhesion-molecule-like domain; mw 211 kD; genbank x82288

Registry number: EC 3.1.3.-

Synonym: nu-3 ptp, ptp nu-3


maturation-promoting factor (medicine)


maturation-promoting factor
<enzyme> A protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms.

In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by cyclins, maturation-promoting factor directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins.

The catalytic subunit of maturation-promoting factor is protein p34cdc2.

Acronym: MPF