See Also: addition-deletion mutation(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Addition(medicine)
addition(dictionary)
Trafalgar(dictionary)
addition(dictionary)
Trafalgar, Cape(dictionary)
Trafalgar, the Battle of(dictionary)
Trafalgar Square(dictionary)
Trafalgar, Battle of(encyclopedia)

addition-deletion mutation (medicine) and Trafalgar (iou)


addition-deletion mutation (medicine)


addition-deletion mutation -->
frameshift mutation
<molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence.

Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons.

Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation.


Trafalgar (iou)



Trafalgar noun. E19.
[A cape on the south coast of Spain, famed for a British naval victory over the combined fleets of France and Spain in 1805.]
I.
Used attrib. to designate things pertaining to or named after (the battle of) Trafalgar. E19.
Trafalgar chair a light graceful Regency chair often decorated with anchors or Other nautical motifs. Trafalgar Day 21 October, the anniversary of the battle of Trafalgar. Trafalgar Square verb phr. trans. (joc.) harangue (from the practice of soap-box oratory in such places as Trafalgar Square in London).
II.
A size of type one size larger than two-line double pica and one size smaller than canon. Now Hist. M19.