See Also: amyloid precursor protein(medicine)
amyloid beta-protein precursor(medicine)
amyloid protein aa(medicine)
amyloid protein saa(medicine)
amyloid protein(medicine)
amyloid beta-protein(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
precursor(medicine)
precursor(dictionary)
precursor(dictionary)

amyloid precursor protein (medicine)


amyloid precursor protein
<protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients.