See Also: autoagglutinin(medicine)
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autoagglutinin (medicine)


autoagglutinin


An agglutinating autoantibody.

Anti-Pr cold autoagglutinin, a cold autoagglutinin specific for the Pr (protease-sensitive) antigen of erythrocytes.

Cold autoagglutinin, a heterogeneous group of autoantibodies that react at temperatures below 37°C, often most actively at 4°C; most are the IgM class of immunoglobulins with affinity for the Ii system of erythrocyte antigens, but some are anti-Pr cold autoagglutinin's; cold autoagglutinin's may be associated with infection (e.g., primary atypical pneumonia, infectious mononucleosis and other virus infections, certain protozoan infections) and in such instances usually are not active in vivo.