See Also: cold haemolysin(medicine)
warm-cold haemolysin(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
A haemolysin(medicine)
Haemolysin(medicine)
b haemolysin(medicine)
specific haemolysin(medicine)
immune haemolysin(medicine)
heterophil haemolysin(medicine)
haemolysin factors(medicine)

cold haemolysin (medicine)


cold haemolysin -->
Donath-Landsteiner cold autoantibody


An autoantibody of the IgG class responsible for paroxysmal cold haemoglobinuria; it is adsorbed to red cells only at temperatures of 20°C or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has only slight agglutinating properties in spite of its marked lytic activity, and has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis.

Synonym: cold haemolysin.