See Also: deoxyribonucleases, type I site-specific(medicine)
deoxyribonucleases, type II site-specific(medicine)
deoxyribonucleases, type III site-specific(medicine)
site-specific DNA methyltransferase (cytosine-specific)(medicine)
site-specific DNA-methyltransferase (adenine-specific)(medicine)
site-specific(dictionary)
site-specific mutagenesis(medicine)
site-specific recombination(medicine)
site specific mutation(medicine)
Deoxyribonucleases(medicine)

deoxyribonucleases, type I site-specific (medicine)


deoxyribonucleases, type I site-specific
<enzyme> Enzyme systems containing three different subunits and requiring ATP, s-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent atpases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognise specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers.

Registry number: EC 3.1.21.3