See Also: central core disease of muscle(medicine)
disease, central core, of muscle(medicine)
muscle, central core disease of(medicine)
central core disease(medicine)
central transactional core(medicine)
muscle relaxants, central(medicine)
Auditory disease, central(health)
central Recklinghausen's disease type II(medicine)
white muscle disease(medicine)
extra-ocular muscle disease(medicine)

disease, central core, of muscle (medicine)


disease, central core, of muscle
<anatomy> One of the conditions that produces 'floppy baby' syndrome. CCD causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). CCD is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1).