See Also: gamma-glutamylcysteine(medicine)
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gamma-glutamate (glutamate gamma-) carboxypeptidase(medicine)
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gamma-glutamylcysteine (medicine)


gamma-glutamylcysteine


A necessary precursor in the biosynthesis of glutathione; contains an isopeptide rather than a eupeptide bond.

Gamma-glutamylcysteine synthetase, an enzyme that catalyses the first step in glutathione biosynthesis, reacting l-glutamate, l-cysteine, and ATP to form gamma-glutamylcysteine, ADP, and orthophosphate; inhibited by thiols such as glutathione.