See Also: hereditary methemoglobinaemic cyanosis(medicine)
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Cyanosis(health)
Cyanosis(medicine)
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late cyanosis(medicine)
cyanosis retinae(medicine)
toxic cyanosis(medicine)
tardive cyanosis(medicine)
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hereditary methemoglobinaemic cyanosis (medicine)
hereditary methemoglobinaemic cyanosis -->
congenital methemoglobinaemia
Methemoglobinaemia due to formation of any one of a group of abnormal a chain or b chain haemoglobins collectively known as haemoglobin M. Slate-gray cyanosis occurs in early infancy, without pulmonary or cardiac disease, and is resistant to ascorbic acid or methylene blue therapy; autosomal dominant inheritance, methemoglobinaemia due to deficiency of cytochrome b5 reductaseor methemoglobin reductase, the enzyme responsible for reduction of intraerythrocyte methemoglobin; cyanosis is improved by ascorbic acid or methylene blue; autosomal recessive inheritance, one case of methemoglobinaemia has been reported that apparently is due to a deficiency of cytochrome b5.
Synonym: hereditary methemoglobinaemia, hereditary methemoglobinaemic cyanosis, primary methemoglobinaemia.
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