See Also: hypoxanthine guanine phosphoribosyltransferase(medicine)
hypoxanthine-guanine-xanthine phosphoribosyltransferase(medicine)
hypoxanthine guanine phosphoribosyltransferase deficiency(medicine)
hypoxanthine phosphoribosyltransferase(medicine)
hypoxanthine-guanine phosphoribosyl transferase(medicine)
hypoxanthine-guanine phosphoribosyl tranferase marker(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
Hypoxanthine(medicine)
hypoxanthine oxidase(medicine)
tRNA-hypoxanthine ribosyltransferase(medicine)

hypoxanthine guanine phosphoribosyltransferase (medicine)


hypoxanthine guanine phosphoribosyltransferase -->
hypoxanthine phosphoribosyltransferase
<enzyme> An enzyme that catalyses the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the lesch-nyhan syndrome, while partial deficiency results in overproduction of uric acid.

Chemical name: IMP:pyrophosphate phospho-D-ribosyltransferase

Registry number: EC 2.4.2.8