See Also: hypoxanthine-guanine phosphoribosyl tranferase marker(medicine)
hypoxanthine-guanine phosphoribosyl transferase(medicine)
hypoxanthine guanine phosphoribosyltransferase(medicine)
hypoxanthine guanine phosphoribosyltransferase deficiency(medicine)
hypoxanthine-guanine-xanthine phosphoribosyltransferase(medicine)
Princes Street(dictionary)
Princes in the Tower, the(dictionary)
phosphoribosyl pyrophosphate(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
N-(5'-phosphoribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase(medicine)

hypoxanthine-guanine phosphoribosyl tranferase marker (medicine) and Princes Street (oh)


hypoxanthine-guanine phosphoribosyl tranferase marker (medicine)


hypoxanthine-guanine phosphoribosyl tranferase marker


The gene which codes for the enzyme hypoxanthine-guanine phosphoribosyl transferase. It is a selectable marker because cells which have a defective version of this gene are resistant to poisoning by toxic purine Derivatives which result from the metabolic pathway that the HGPRT enzyme catalyses. (The purine Derivatives are toxic because they incorporate into DNA as a result of the HGPRT enzyme's actions). Because the defective gene cannot produce the enzyme, no toxic purine Derivatives are produced, the gene can therefore be selected for.


Princes Street (oh)



the main street in Edinburgh, Scotland, with many shops and banks