See Also: infantile GM2 gangliosidosis(medicine)
infantile generalised GM1 gangliosidosis(medicine)
Herbal medicine (botanical medicine, herbology, phytomedicine)(health)
GM1 gangliosidosis(medicine)
GM2 gangliosidosis(medicine)
gangliosidosis g(m1)(medicine)
gangliosidosis(medicine)
generalised gangliosidosis(medicine)
Type 1 GM1 gangliosidosis(medicine)
B variant GM2-gangliosidosis(health)
infantile GM2 gangliosidosis (medicine)
infantile GM2 gangliosidosis -->
Tay-Sachs disease
<disease> A genetic disorder found in east European Jewish families which can result in early death bu affecting the brain and nerves by causing abnormal lipid metabolism. It is a lysosomal disease in which there is a deficiency of hexosaminidase A, an enzyme that degrades ganglioside GM2.
Symptoms appear at age 3-6 months and include blindness, deafness, seizures, paralysis, dementia, decreased muscle tone and growth retardation. There is no known treatment and most children usually die between 2 and 5 years of age.
Inheritance: autosomal recessive.
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