See Also: isocitric acid dehydrogenase(medicine)
isocitric acid(medicine)
13-hydroxyoctadecadienoic acid dehydrogenase(medicine)
norsolorinic acid dehydrogenase(medicine)
tropic acid dehydrogenase(medicine)
malic acid dehydrogenase(medicine)
iminodiacetic acid dehydrogenase(medicine)
lactic acid dehydrogenase(medicine)
glycolic acid dehydrogenase(medicine)
4-pyridoxic acid dehydrogenase(medicine)

isocitric acid dehydrogenase (medicine)


isocitric acid dehydrogenase -->
isocitrate dehydrogenase
<enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.)

Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating)

Registry number: EC 1.1.1.41