See Also: saccharopine dehydrogenase(medicine)
saccharopine(medicine)
saccharopine dehydrogenases(medicine)
saccharopine oxidase(medicine)
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saccharopine dehydrogenase (medicine)


saccharopine dehydrogenase


Two enzymes that are used in the pathway of l-lysine catabolism; the first isoform catalyses the reversible conversion of l-lysine, alpha-ketoglutarate, and NADH to saccharopine and NAD+; the other isoform reversibly catalyses to conversion of saccharopine and NAD+ to l-glutamate, NADH, and l-alpha-aminoadipate d-saemialdehyde. A deficiency of one of these isoforms is associated with familial hyperlysinaemia and saccharopinuria.